Unlike in previous years when teams reduced their rosters from 90 to 75 players before their final preseason game and then to a 53-man squad after it, there is only one cut-down day this year.
The 49ers, who currently have 89 players on the active roster, must be down to 53 players by 1 p.m. Saturday. That will allow them to keep most of their starters and older veterans out of the finale vs. the Chargers but will cause a mad scramble as teams try to evaluate 1,184 (or so) castoffs over the weekend.
If none of those castoffs are added, here's my guess on how the 49ers get to 53.