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49ers final injury report has three notable question marks

Friday marked the last full practice of the week for the San Francisco 49ers as they prepare for their Week 8 matchup against the Arizona Cardinals. Coach Kyle Shanahan spoke to the media and relayed Friday’s injury report, featuring some notable updates that will impact the 49ers’ starting lineup come Sunday.

Running back Matt Breida returned to practice Friday in limited fashion after sitting out most of the week with a persistent ankle injury. The 49ers’ leading back has been battling the injury for weeks, forcing him to make an early exit against the Rams in Week 7.