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49ers end 10-game losing streak to Seahawks with 26-23 overtime win

San Francisco 49ers' Garrett Celek (88) celebrates his 2nd quarter touchdown with teammates while playing Seattle Seahawks during NFL game at Levi's Stadium in Santa Clara, Calif. on Sunday, December 16, 2018.

San Francisco 49ers' Garrett Celek (88) celebrates his 2nd quarter touchdown with teammates while playing Seattle Seahawks during NFL game at Levi's Stadium in Santa Clara, Calif. on Sunday, December 16, 2018.

Photo: Scott Strazzante / The Chronicle

The 49ers had a holding penalty on the game’s opening kickoff Sunday.

They lost starting cornerback Ahkello Witherspoon to a knee injury on their sixth defensive snap.