We're back for another week of the 2015 NFL season, which means another look at San Francisco 49ers predictions. The team is back home to face another division rival in the Arizona Cardinals. The game is Sunday afternoon at 1:05 p.m. PT on FOX.
Once again, it is time for more predictions for Sunday's game. I posted the Week 12 prediction contest thread, so you can get all of your picks in there, but we can focus on 49ers-specific picks in here. The 49ers were thumped by the Arizona Cardinals in Week 3, but the 49ers also opened that game with a pair of pick-sixes, so they were behind the curve pretty quickly.