The San Francisco 49ers will travel to Pittsburgh to open their 2023 campaign to take on the Pittsburgh Steelers. Sunday will mark the 23rd meeting between the two teams. San Francisco holds the edge in the series having won 12 of the previous 22 matchups, including six of the 11 games in the Steel City.
San Francisco and Pittsburgh last met in week three of the 2019 season. Despite several offensive miscues, the 49ers were able to pull out a come from behind 24-20 victory at Levi’s Stadium.
Sunday will mark the first time since 2014 the Steelers have opened their season at home.