The San Francisco 49ers are in Houston this week, holding joint practices with the Texans on Wednesday and Thursday, and then squaring off in a preseason game on Saturday. The line for the game opened at a handful of oddsmakers with the Texans as 1.5 point favorites. Since then, most have climbed to 2.5 points, and additional sports books simply opened the line at 2.5 points as of Tuesday morning, according to Odds Shark. The point total is set at 41.
The big question will be how much the starters will play in this second preseason game for each team.