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3 keys to a 49ers victory over the Cardinals: It’s all about keeping Garoppolo clean

The San Francisco 49ers face the Arizona Cardinals in Mexico City for Week 11’s Monday Night Football. Surprisingly, Kyle Shanahan holds a 3-3 record against Arizona since Kliff Kingsbury was named head coach in 2019. However, that could change tonight, and here are three reasons why it will.

Disciplined defense

DeMeco Ryans instantly became a hot commodity when he took over defensive play-calling duties last year. Ryans’ witty defense will earn him a head coaching job. In addition, he greatly impacts the success of San Francisco by adding his wrinkles to Robert Saleh’s defense.