Robinson Cano took Padres starter Christian Friedrich deep in the top of the first inning, giving the Mariners a three-run lead before an out was recorded. But Friedrich settled in nicely after that, tossing five frames while allowing only those three earned runs and another unearned run in the fourth.
Paxton wasn't quite as adept at limiting the damage. Filling in for Felix Hernandez -- who hit the disabled list Wednesday afternoon -- Paxton allowed eight runs (only three of them earned) on 10 hits in 3 2/3 frames.
MOMENTS THAT MATTERED
Padres make 'em pay: Following Myers' solo homer, the Padres tacked on five more runs in the opening frame -- all of them unearned.