With the season entering its final month, they remain the biggest part of the Padres lineup.
"I think the whole offense should feel pretty good about themselves today," Padres interim manager Pat Murphy said. "If we want to win, it's about our big guys coming up big. They did today and that really set everything up."
Upton has been in a groove as of late and his solo shot in the third with two outs extended the Padres lead to 3-1 against Phillies rookie starter Alec Asher. Upton's fourth home run in five games gave him 24 for the year and he became the first Padres outfielder to reach 24 home runs in a season since Bubba Trammell hit 25 in 2001.