The San Antonio Spurs are almost certainly not going to win against the Denver Nuggets.
I feel that I should get that out of the way now. There were already, conceivably, very few scenarios in which the Spurs would be likely to beat the Nuggets in a fair (or even unfair) contest. The Nuggets lead the entirety of the Western Conference and are also vying for best record in the NBA this season.
The Nuggets have six players worth 3+ WAR, the Spurs have none. The Nuggets have six players with a positive +/- on the season, the Spurs have none.