Rick Pitino is PISSED after a couple of crooks allegedly broke into his St. John's office and jacked some of his keepsakes ... mostly because the haul included a bottle of wine that comes with an eye-popping price tag.
Two men found their way into the legendary coach's Carnesecca Arena quarters around 6 PM on Tuesday ... and snagged "various items" before fleeing the area on a moped, NYPD said in a statement.

Wine O'Clock?