Cycling star Daniel Oss is out of the Tour de France ... after the Italian fractured his neck in an insane, high-speed crash with a fan during the race on Wednesday.
Oss' team, Total Energies, made the announcement on Thursday -- the day after the 35-year-old smashed into a spectator on the side of a racing path.
The collision was captured on video ... and you can see Oss -- in a white helmet and racing gear -- flying down the edge of the cobblestone lane before he brutally collided with the bystander who was trying to record the race on their phone.