DeAndre Hopkins' mom is getting a movie made about her inspirational life ... and now, the Houston Texans superstar is giving TMZ Sports his perfect fit for her role -- Oprah!
If ya missed it ... Sabrina Greenlee is set to be the subject of a new Hollywood picture -- 'cause her story is amazing.
Back in 2002, she was ambushed by a woman who threw a dangerous mixture of drain cleaner and Clorox bleach at her face ... which blinded her immediately.
The attack nearly killed her -- and sent her into deep depression afterward -- but she battled back to be an awesome mother and an active community leader.