The first time these division rivals met, a last-second call on an end zone catch (or no-catch) was the deciding factor in the outcome of the game. A possible Los Angeles Chargers touchdown was overturned and ruled out of bounds, giving the Las Vegas Raiders the road win.
Now these AFC West challengers will have their rematch in Vegas, as the Chargers look to get even. The experts have already weighed in with their picks, which can be found below.
CBS Sports picks are from their panel of experts, numberFire picks are from their NFL game projections, Sporting News picks are from Vinnie Iyer and betting favorites are from FanDuel Sportsbook's Week 15 NFL odds.