Brianna LaPaglia doesn't care what's in the orange ... 'cause she's clearly tired of hearing Zach Bryan's voice in any capacity -- booing when his iconic track came on at UFC 309.
The Barstool Sports personality -- better known by her nickname Brianna Chickenfry -- hit up Madison Square Garden in New York City for fight night Saturday ... when the venue started playing Bryan's "Something in the Orange."
LaPaglia's clearly not happy with the song choice .