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2 Chainz's Ex-Manager

"Lose 120 pounds and become an Ironman ... after beating a brain tumor."

Damn impressive, right?

Colin Kaepernick thought so ... and that's why Charlie Jabaley was picked to be featured in Kaep's new Nike commercial.

Believe in something. Even if it means sacrificing everything. #JustDoIt pic.twitter.com/x5TnU7Z51i

— Colin Kaepernick (@Kaepernick7) September 5, 2018

Charlie used to be 300 pounds. He also used to manage rap stars like 2 Chainz and Travis Porter -- but quit his job to focus on health when doctors told him a brain tumor from his youth had come back.