Mauricio Pochettino insists Jan Vertonghen is fit and ready to alleviate Tottenham's "mistake" of omitting Juan Foyth from their Champions League roster.
Spurs must beat Inter at Wembley on Wednesday to have any hope of leapfrogging the Serie A side into second spot in Group B.
Belgium defender Vertonghen has not played a minute since injuring his hamstring against Huddersfield Town two months ago, but was named among the substitutes for the Premier League win over Chelsea and is now likely to be thrust into the starting XI.
Editors' Picks
Foyth, a regular in recent fixtures, is ineligible after missing out on the 25-man squad chosen for the group stage in September, while Davinson Sanchez is battling a hamstring problem of his own.