Tottenham came away from St Mary's with three points as Harry Kane, Son Heung-min and a double by Dele Alli ensured a happy return for Mauricio Pochettino.
Southampton opened the scoring when Virgil van Dijk scored within the first two minutes before Alli levelled before the break.
Tottenham then eased to victory as Nathan Redmond saw red for hacking down Alli to gift Spurs a penalty.
Here, Sportsmail picks out five things you may have missed during the Premier League match in case you had to pop to the kitchen to make a cup of tea or were busy tweeting your opinions on the 4-1 win for Tottenham.