SuperSport United will lock horns with their Gauteng rivals Orlando Pirates in a Premier Soccer League (PSL) match at the Mbombela Stadium on Wednesday.
Matsatsantsa are wounded after beginning the 2019/20 season with a 2-0 loss to Mamelodi Sundowns in the Tshwane Derby clash almost two weeks ago.
The Tshwane giants are keen to compete for the league title this season after enduring a disappointing 2018/19 campaign, in which they ended trophyless.
Meanwhile, Pirates started their domestic campaign with a 3-1 win over Bloemfontein Celtic, but they were stunned by Zambian side Green Eagles in the Caf Champions League clash over the weekend.