BBC Sport football expert Chris Sutton said: "It's the game of the season so far, but is City striker Erling Haaland fit? Who knows.
"We will have to wait until we see the teams to be sure either way, which makes it a bit of a nightmare to make my prediction now. It doesn't help fantasy football managers very much either - but I have still got him as my captain."
Sutton is making predictions for all 380 Premier League matches again this season, against a variety of guests.
This week, he takes on Barry Can't Swim, aka DJ and producer Joshua Mannie - who is an Everton fan.