David Silva is a doubt for Manchester City after limping off during the FA Cup semi-final defeat to Arsenal.
Sergio Aguero, who also picked up a knock in that game, is fit to play. Gabriel Jesus is ready after recovering from a broken foot but Pep Guardiola says his condition is "not optimal".
Manchester United are without Paul Pogba due to a muscle injury, but Ander Herrera has overcome an ankle knock.
Chris Smalling and Phil Jones remain sidelined with knee and toe injuries.
COMMENTATOR'S NOTES
Guy Mowbray: "When City won the league in 2012, some predicted a strong shift to the blue side in Manchester's balance of power.