Manchester United midfielder Kobbie Mainoo will be out for a "few weeks" with a muscle injury.
The 19-year-old England international suffered the problem during United's 0-0 Premier League draw at Aston Villa and subsequently withdrew from the Three Lions squad for their two Nations League games last week.
Defender Harry Maguire has also been ruled out for a similar timescale after also picking up an injury at Villa Park.
However, Noussair Mazraoui has returned to training following a recent medical procedure after suffering heart palpitations.
The Morocco international underwent a precautionary, minor corrective procedure to rectify a relatively common condition last week.