Luton Town have no fresh injury concerns and new signing Daiki Hashioka could be included for the first time.
Mads Andersen, Marvelous Nakamba and club captain Tom Lockyer remain the only long-term absentees.
Manchester United remain optimistic on Luke Shaw's availability after he was withdrawn at half-time last weekend.
Aaron Wan-Bissaka suffered a knock in training and will join Tyrell Malacia, Anthony Martial, Lisandro Martinez and Mason Mount on the sidelines.
MATCH FACTS
Head-to-head
- Luton Town have failed to win any of their past 12 matches against Manchester United in all competitions, drawing two and losing 10.