After a dramatic round of midweek fixtures, Liverpool must wait until Monday night for the chance to maintain or extend their lead at the top of the Premier League table.
The Reds were left frustrated as their draw at home to Leicester on Wednesday denied them the chance to take full of advantage of Manchester City's defeat at Newcastle 24 hours earlier.
The gap to City, then, remains five points when it might have been seven, and Liverpool could well be under pressure by the time they take to the field at the London Stadium.
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West Ham have provided little threat in the last two seasons, with Jurgen Klopp's men winning 4-0 and 4-1 in this fixture, but with nerves jangling among Reds supporters, this promises to be another stern test.