Islam Slimani has been ruled out of Monaco's clash against Stade de Reims in Saturday’s Ligue 1 game due to a calf strain.
The 31-year-old Algeria striker has scored three goals in three league games since his summer loan move from Premier League side Leicester City.
Leonardo Jardim’s men will also miss the services of Slimani’s strike partner Wissam Ben Yedder due to a hip injury.
The attacking duo will be replaced by Jean-Kevin Augustin and Senegal international Keita Balde for the encounter with David Guion’s men.