Everton manager Ronald Koeman is expected to give a debut to new signing Morgan Schneiderlin following his £20m-plus move from Manchester United.
They remain without a host of players, including Muhamed Besic, Yannick Bolasie, Dominic Calvert-Lewin, Idrissa Gueye and Maarten Stekelenburg.
Manchester City boss Pep Guardiola is still without the banned Fernandinho.
Vincent Kompany and Leroy Sane are doubts, while Ilkay Gundogan is a long-term absentee.
MOTD COMMENTATOR'S NOTES
Guy Mowbray: "Starter? Support card? Look beyond purely rivalry issues and you'll see a contest bursting with as much interest as 'the other one' on Sunday.