Everton left-back Leighton Baines should be fit after recovering from the back problem he suffered last weekend.
Muhamed Besic lacks fitness after a lengthy lay-off and James McCarthy, who has a hamstring injury, is also out.
Hull are without Everton loanee Oumar Niasse, who is ineligible against his parent club, while Evandro is again absent with a calf problem.
Markus Henriksen is back in training after a shoulder injury but is unlikely to feature on Saturday.
Michael Dawson, Dieumerci Mbokani and Ryan Mason remain sidelined.
MOTD COMMENTATOR'S NOTES
Steve Wilson: "Romelu Lukaku is poised to become the first Evertonian to hit 20 league goals in a season since Gary Lineker - unfortunately he may also be poised for a Goodison exit.