Liverpool have dominated proceedings against Merseyside rivals Everton in the two most recent decades, but the latest Premier League instalment of the derby could throw up the most thrilling encounter between the two sides for years.
Not since September 1999 have the Toffees recorded a top-flight victory at Anfield, when Kevin Campbell scored in the fourth minute to net the only goal of the game.
The game also saw Steven Gerrard's first career red card but his former side have ruled the roost against Everton since then in an unbeaten run at Anfield, winning 11 and drawing the other nine top-flight clashes.