In-form winger Daniel James will miss Manchester United's first Europa League group-stage match against Astana through injury.
Ole Gunnar Solskjaer confirmed Wales international James suffered a "knock" against Leicester City at the weekend and would sit out Thursday's game at Old Trafford.
The 21-year-old skipped United's final training session before the Group L fixture and joins Paul Pogba, Anthony Martial and Luke Shaw on the sideline.
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Jesse Lingard and Diogo Dalot are ready to return from illness and a hip problem respectively.
"He got a knock against Leicester so he won't be available," Solskjaer said of James.