Emmanuel Dennis' goal against Manchester United ended the English impressive defensive record.
Dennis gave Club Brugge a 15th minute lead after connecting to Simon Mignolet's goal kick to beat a stranded Sergio Romero.
Nine minutes before the half-time break, Anthony Martial scored the equaliser as the Europa League encounter ended 1-1 at the Jan Breydel Stadium.
The Nigerian's effort ended the Red Devils' run of 408 minutes without conceding across all competitions.
Ole Gunnar Solskjaer's side last conceded a goal in their 2-0 home defeat to Burnley on January 22.