Brentford have opened talks with Gremio over a £9.5million deal for Brazilian right back Vanderson.
The Premier League side have watched the defender for some time and tried to sign him in August when Gremio were looking for £13.5m.
The 20-year old has yet to be capped by Brazil at full international level and the move will be subject to a work permit.
Vanderson is strong going forward and good at taking set pieces.
Brentford have made an excellent impact on their first season in the Premier League and owner Matthew Benham is keen to strengthen the squad ahead of the second half of the season.