The Swiss champions, currently second in their domestic league, face their sternest challenge of the season so far
Manchester City begin their Champions League knock-out journey fresh in the knowledge that they have a 16-point gap between themselves and cross-town rivals United in the Premier League.
As such, Pep Guardiola can afford to field his strongest side against one of the lesser lights left in Europe's top club competition in FC Basel.
The Catalan coach will be further buoyed by Sergio Aguero's four-goal performance against Leicester at the weekend, with Gabriel Jesus still unavailable through injury.