Pep Guardiola is set to be without his star striker for four games, Brazilian midfield enforcer for three and his Spanish centre-half for one fixture
The Football Association has confirmed that Manchester City trio Sergio Aguero, Fernandinho and Nicolas Otamendi are to serve four, three and one-match bans respectively.
Aguero is facing four games on the sidelines following his red card against Chelsea on Saturday.
The Argentina international was sent off for a reckless challenge on David Luiz in injury time of Manchester City's 3-1 defeat to the Premier League leaders at the Etihad Stadium.
The FA updated the disciplinary page on their official website on Monday, verifying that Aguero has been given a suspension that will rule him out of matches against champions Leicester City, Watford, Arsenal and Hull City.