Oliver Giroud will hope to start his first league game of the season after scoring in Arsenal's last two matches.
Santi Cazorla and Hector Bellerin remain sidelined, while the game comes too soon for Lucas Perez, who is back in training after an ankle problem.
Bournemouth's Artur Boruc and Andrew Surman are doubts with respective back and hamstring problems, while Gunners loanee Jack Wilshere is ineligible.
Adam Smith is back after a ban and Jordon Ibe returns following illness.
MOTD COMMENTATOR'S NOTES
Simon Brotherton: "Arsenal are unbeaten in 18 matches since the opening weekend and sit just three points off the top of the table heading into the latest round of fixtures, but the mood around the Emirates hardly seems one of optimism unbounded.