The Pittsburgh Steelers will play their fifth game of the 2022 regular season on Sunday afternoon against the Buffalo Bills, and that road game will take place at Highmark Stadium. On Tuesday, the official start of Week 5, the Steelers are consensus 14-point underdogs to the Bills, according to vegasinsider.com. The consensus over/under point total for the contest is 47 as of Tuesday morning.
The Bills, who are coached by Sean McDermott, enter Week 5 with a 3-1 record following a Week 4 road win against the Baltimore Ravens and a Week 3 road loss to the Miami Dolphins.