The Buffalo Bills were part of the American Football League that was set up in 1960 to rival the NFL. Ten years later both leagues merged and the Pittsburgh Steelers and Bills have met 26 times since. Pittsburgh has won 16 of those games while the Bills have the edge in Buffalo 7-6.
In the seventies, while the Steelers were winning four Super Bowls they dominated the exchanges 5-1. The following decade saw the Bills reverse the position as they won four while the Steelers could only muster the one win.
The nineties saw the teams split the series 4-4 before the Steelers regained control at the turn of the century winning six before losing 17-10 last year.