Phillies left-hander Adam Morgan, who is competing for a job in the rotation, pitched three scoreless frames, walking one batter and allowing a hit to Niese.
Niese gave up four runs on two hits with two walks in three innings. He has permitted eight runs over five innings in two Grapefruit League starts.
Cole Figueroa and prospect Harold Ramirez produced back-to-back RBI singles off Chris Leroux in the seventh to break up the shutout.