Jameson Taillon was rolling before heading into that faithful frame, but lost the lead when Jose Peraza lead off the inning with a solo shot to left. He was pulled after surrendering a walk to Tucker Barnhart and a line hugging double to Jose Iglesias, and pinch-hitter Derek Dietrich took Richard Rodriguez deep to give the Reds a 5-2 advantage.
Taillon (0-1) finished with four earned runs on his ledger in 6+ innings. He struck out four, walked two and allowed a homer.
The Pirates struck for two runs in the sixth on a base hit by Jung-Ho Kang, with Francisco Cervelli scoring all the way from first via an aggressive send by third base coach Joey Cora.