The NFL Week 1 slate of Sunday games will cap off with a Sunday Night Football matchup between the Los Angeles Rams on the road against the Detroit Lions.
The Rams lead the all-time series between these AFC teams, 45-40-1, and have won three of the four most recent matchups. They haven’t faced off in the regular season since 2021, when the Rams won at home in Los Angeles, 28-19. While the Rams have the lead in the regular season, the Lions are 2-0 against the Rams in the playoffs, most recently winning back in January during the wild card round, 24-23.