According to Coach Pederson, OL Allen Barbre (hamstring), WR Jordan Matthews (ankle), RB Darren Sproles (concussion protocol) and T Halapoulivaati Vaitai (knee) will all sit out from practice on Wednesday. Pederson says that the hope is that Barbre, Matthews and Sproles will all be ready to play on Sunday.
As a precaution, the Eagles will practice with rookie third-round pick Isaac Seumalo at right tackle while Barbre recovers. If everything goes to plan, Stefen Wisniewski will start at left guard, Brandon Brooks will start at right guard, and Barbre will start at right tackle with Seumalo as an insurance policy.