The big change to the Eagles offense will come at right tackle, where rookie Halapoulivaati Vaitai replaces the suspended Lane Johnson. The line has been a strength this season because of the way Johnson has played, so his absence could affect both the running and passing games. The good news for the Eagles is they're playing against one of the worst run defenses in the NFL. Washington allows 130 rushing yards per game and a league-worst 5.1 yards per carry. If there was ever a game for Ryan Mathews to break out, it's this one. Mathews, who missed practice Friday because of an illness, is averaging only 3.