The Eagles will open the 2016 regular season with a home game against the Cleveland Browns. That hasn't happened since 1969, the first game of the Leonard Tose era. It has happened only five times in franchise history. Interestingly, two of them occurred when the Eagles were the defending world champions.
In 1950, the Eagles were coming off back-to-back championships and NFL Commissioner Bert Bell scheduled them to open the season against the Browns who were joining the NFL after dominating the rival All-America Football Conference. It was not a coincidence that the two teams met in the opener.