Since becoming conference rivals Washington is 6-0 both straight up and against the spread in six meetings with Colorado, winning those games by an average score of 44-13. The Huskies shoot to make it seven in a row over the Buffaloes on Saturday afternoon in Seattle.
College football point spread: The Huskies opened as 16.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 41.5-24.9 Huskies (College football picks on every game)
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