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Coaches: Brian Flores is 16-17 in his third season with Dolphins; Sean McDermott is 40-31, including playoffs, in his fifth season leading the Bills.
Series: The Dolphins have a 61-52-1 edge in the all-time series, including postseason, but the Bills have won five straight over the Dolphins.
Noteworthy: The first-place Miami Dolphins — they are 1-0 while the rest of the AFC East is 0-1 — can firmly put themselves at the forefront of the division with a home win over the AFC East-favorite Buffalo Bills.