City pays FC Dallas a visit for the first time in two years. The match can be viewed on TV27 or YouTube 27.
James O'Connor shakes up the backline pairing Lamine Sané with Shane O'Neill.
Meanwhile, Peruvians Yoshimar Yotún and Carlos Ascues team up in the holding midfield positions. Further up the pitch, Sacha Kljestan will wear the Captain's armband in Jonathan Spector's absence.
The start for Chris Mueller makes it his 30th appearance on the season. That's the first time a City rookie has reached 30 appearances in a season.
Starting XI presented by Orlando Health: Bendik, El-Munir, Sané, O'Neill, Sutter, Yotún, Ascues, Mueller, Kljestan, Johnson, Dwyer.