The central problem Oregon has is that the offensive line has gone from its greatest strength to its greatest weakness. It means that they can’t establish the run and make 2nd & 3rd downs manageable, and when they have to pass to make up for it, throws are constantly hurried by pressure.
Here’s how the run game currently looks (reminder - you can right-click or long-press any of these videos to slow them to ¼ or ½ speed):
On the first play, two backups -- #66 RT Aiello and #71 RG Capra -- trip over each other when sealing the edge.