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The United States lost the men's 4x100-meter mixed relay for the first in Olympic history on Sunday.
The Americans came up just short with a silver-medal performance to China.
China received an incredible 45.92-second split from 100-meter freestyle gold medalist Pan Zhanle to take home gold.
Caeleb Dressel and Hunter Armstrong delivered impressive splits of their own in the final two legs for the United States to take second place ahead of France.
Results
1. China - 3:27.46
2. United States - 3:28.