Fifth-ranked Oklahoma faces Iowa State at 11 a.m. Saturday in Ames, Iowa. Here's what to look for:
3 Players to Watch
Trey Sermon: Sermon is now Oklahoma's lead running back after the Sooners lost Rodney Anderson to a season-ending knee injury. The sophomore from Marietta, Ga., made three starts last season.
Kyler Murray: The junior quarterback has met if not exceeded expectations through the first two weeks, but it's worth watching how Murray handles his first road start.
Neville Gallimore: The 6-foot-2, 330-pound nose guard is the anchor in the middle of Oklahoma's 3-4 defensive front.