The Sooners committed a season-high 25 turnovers against the visiting Cyclones, who turned those two dozen miscues on the OU offensive end into 31 Iowa State points and a 92-87 win at Lloyd Noble Center in Norman.
Oklahoma held a 19-point first-half lead at 28-9, but once again was unable to hold on as the Cyclone outscored OU 21-1 over the final eight minutes of the first half, allowing Iowa State to take a one-point lead, 30-29, into halftime.
Failing to hold on to that nearly 20-point advantage early in the game eventually proved to be the difference maker in the game.