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2022 NCAA Tournament Preview: Sweet 16 - Iowa State in the Final Four would be gross (and more)

No time to waste – let’s break down the four regions in what usually turns into the best weekend of the NCAA Tournament.

Midwest Region

What did we do to deserve this?

We hit on our pick for the Cyclones to upset a discombobulated LSU team in the first round. Unfortunately, that meant ISU could continue playing, setting up its knockout of Wisconsin in the second round. One lackluster team losing to an even more uninspiring one.

After winning just two games in 2020, the Cyclones made an impressive turnaround this season under new head coach T.